(S)-1-(5-bromo-6-(1-methoxyethyl)pyridin-3-yl)-4-(2-(methylsulfonyl)ethyl)piperazine

(S)-4-(1-((5-bromo-6-(1-methoxyethyl)pyridin-3-yl)ethynyl)cyclopropyl)-1,4-oxazepane

(S)-4-((5'-bromo-6'-(1-methoxyethyl)-[2,3'-bipyridin]-6-yl)methyl)morpholine

(S)-4-((5'-bromo-6'-(1-methoxyethyl)-[3,3'-bipyridin]-6-yl)methyl)morpholine

(S)-4-(5-(5-bromo-6-(1-methoxyethyl)pyridin-3-yl)pyrimidin-2-yl)morpholine

(S)-tert-butyl 3-(3-(5-bromo-6-((S)-1-methoxyethyl)pyridin-3-yl)isoxazol-5-yl)morpholine-4-carboxylate

(S)-tert-butyl 4-(3-(5-bromo-6-(1-methoxyethyl)pyridin-3-yl)isoxazol-5-yl)piperidine-1-carboxylate

(8R,9aS)-8-(5-bromo-6-((S)-1-methoxyethyl)pyridin-3-yl)octahydropyrido[2,1-c][1,4]oxazine

(8S,9aR)-8-(5-bromo-6-((S)-1-methoxyethyl)pyridin-3-yl)octahydropyrido[2,1-c][1,4]oxazine

(S)-5-(5-bromo-6-(1-methoxyethyl)pyridin-3-yl)-N,N-dimethylpyrimidin-2-amine

(S)-4-(3-(5-bromo-6-(1-methoxyethyl)pyridin-3-yl)prop-2-yn-1-yl)morpholine

(7R,14R)-11-chloro-6-methyl-5-oxo-5,6,7,14-tetrahydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-1-yl trifluoromethanesulfonate

(7R,14R)-11-(6-((1R,2S)-1-amino-2-methylcyclobutyl)-5-fluoropyridin-3-yl)-1-(difluoromethoxy)-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(1R,3r)-3-(5-((7R,14R)-1-(difluoromethoxy)-6-((1-fluorocyclopropyl)methyl)-5-oxo-5,6,7,14-tetrahydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-11-yl)pyrimidin-2-yl)-1-(fluoromethyl)-3-hydroxycyclobutanecarbonitrile

(1R,3r)-3-(5-((7R,14R)-1-(difluoromethoxy)-6-(2-fluoroethyl)-5-oxo-5,6,7,14-tetrahydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-11-yl)pyrimidin-2-yl)-1-(fluoromethyl)-3-hydroxycyclobutanecarbonitrile

(7R,14R)-11-(2-(1-aminocyclobutyl)pyrimidin-5-yl)-1-(difluoromethoxy)-6-((1-fluorocyclopropyl)methyl)-5-oxo-5,6,7,14-tetrahydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocine-4-carbonitrile

(7R,14R)-11-(2-(1-aminocyclobutyl)pyrimidin-5-yl)-1-(difluoromethoxy)-6-(furan-2-ylmethyl)-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(1R,3r)-3-(5-((7R,14R)-1-(difluoromethoxy)-6-(((1S,2S)-2-fluorocyclopropyl)methyl)-5-oxo-5,6,7,14-tetrahydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-11-yl)pyrimidin-2-yl)-1-(fluoromethyl)-3-hydroxycyclobutanecarbonitrile

(1R,3r)-3-(5-((7R,14R)-1-(difluoromethoxy)-6-(((1R,2R)-2-fluorocyclopropyl)methyl)-5-oxo-5,6,7,14-tetrahydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-11-yl)pyrimidin-2-yl)-1-(fluoromethyl)-3-hydroxycyclobutanecarbonitrile

(1R,3s)-1-(cyclopropylmethyl)-3-(5-((7R,14R)-1-(difluoromethoxy)-6-methyl-5-oxo-5,6,7,14-tetrahydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-11-yl)pyrimidin-2-yl)-3-hydroxycyclobutanecarbonitrile