4-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)cyclohexanecarboxylic acid

4-(((4-amino-4-methylcyclohexyl)amino)methyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

5-(((2-aminocyclopentyl)methyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

5-(((2-aminocyclobutyl)amino)methyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

4-(((4-aminobutan-2-yl)amino)methyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

4-((benzyl(methyl)amino)methyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

4-((cyclohexylmethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

(7R,14R)-1-(difluoromethoxy)-11-((S)-5,6-dihydrospiro[cyclopenta[b]pyridine-7,2'-pyrrolidin]-3-yl)-6-methyl-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(7R,14R)-1-(difluoromethoxy)-11-((R)-4-(fluoromethyl)-4-hydroxy-3,4-dihydro-2H-pyrano[3,2-b]pyridin-7-yl)-6-methyl-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

4-(((3-aminopropyl)(methyl)amino)methyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

4-(((3-aminopropyl)amino)methyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

(7R,14R)-1-(difluoromethoxy)-11-(8-hydroxy-5-methyl-5,6,7,8-tetrahydro-1,5-naphthyridin-3-yl)-6-methyl-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(7R,14R)-1-(difluoromethoxy)-11-(3-hydroxy-3-methyl-2,3-dihydrofuro[3,2-b]pyridin-6-yl)-6-methyl-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(7R,14R)-1-(difluoromethoxy)-11-(3-hydroxy-2,3-dihydrofuro[3,2-b]pyridin-6-yl)-6-methyl-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(7R,14R)-1-(difluoromethoxy)-11-[4-(dimethylphosphinyl)-2,3-difluorophenyl]-6,7-dihydro-6-methyl-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-1-(difluoromethoxy)-11-[4-(dimethylphosphinyl)-2,5-difluorophenyl]-6,7-dihydro-6-methyl-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-1-(difluoromethoxy)-11-(4-hydroxy-2,2,4-trimethyl-3,4-dihydro-2H-pyrano[3,2-b]pyridin-7-yl)-6-methyl-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(7R,14R)-1-(difluoromethoxy)-11-(6,7-dihydro-7-oxo-5H-cyclopenta[b]pyridin-3-yl)-6,7-dihydro-6-methyl-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-1-(difluoromethoxy)-11-[2-[1-(dimethylamino)-1-methylethyl]pyrimidin-5-yl]-6,7-dihydro-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-1-(difluoromethoxy)-11-[2-[(dimethylphosphinyl)methoxy]thiazol-5-yl]-6,7-dihydro-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one