4-((R)-2-(aminomethyl)pyrrolidin-1-yl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

4-(((4-aminopentan-2-yl)amino)methyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

5-(((2-aminobutyl)amino)methyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

4-((S)-3-aminopyrrolidin-1-yl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

(7R,14R)-1-(difluoromethoxy)-11-((S)-3-ethyl-3-hydroxy-2,3-dihydrofuro[3,2-b]pyridin-6-yl)-6-methyl-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(7R,14R)-1-(difluoromethoxy)-11-[4-(dimethylphosphinyl)-3-fluorophenyl]-6,7-dihydro-6-methyl-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

5-(((2-azaspiro[3.3]heptan-6-ylmethyl)amino)methyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

4-(((3-aminocyclopentyl)(methyl)amino)methyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

4-(((2-aminocyclopentyl)methyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

4-(((3-amino-3-methylbutyl)amino)methyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

5-(((2-aminophenyl)amino)methyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

(7R,14R)-1-(difluoromethoxy)-11-(4-ethyl-4-hydroxy-3,4-dihydro-2H-pyrano[3,2-b]pyridin-7-yl)-6-methyl-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(7R,14R)-1-(difluoromethoxy)-11-(4-hydroxy-2-methyl-3,4-dihydro-2H-pyrano[3,2-b]pyridin-7-yl)-6-methyl-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(7R,14R)-1-(difluoromethoxy)-11-[4-(dimethylphosphinyl)-2-fluorophenyl]-6,7-dihydro-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-1-(difluoromethoxy)-11-[2-[1-[[(tert-butyl)dimethylsilyl]oxy]-1-methylethyl]pyrimidin-5-yl]-5,14-dihydro-5-oxo-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocine-6(7H)--acetic acid ethyl ester

(7R,14R)-1-(difluoromethoxy)-11-(5',6'-dihydrospiro[azetidine-2,7'-cyclopenta[b]pyridin]-3'-yl)-6-methyl-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(7R,14R)-1-(difluoromethoxy)-11-[2-(1,1-dioxido-4-thiomorpholinyl)-pyrimidin-5-yl]-6,7-dihydro-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-1-(difluoromethoxy)-11-[4-(difluoromethyl)-2-(1-hydroxy-1-methylethyl)-pyrimidin-5-yl]-10-fluoro-6,7-dihydro-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-1-(difluoromethoxy)-11-(2,3-dihydro-2-oxo-1H-pyrrolo[2,3-b]pyridin-5-yl)-6,7-dihydro-6-methyl-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-1-(difluoromethoxy)-11-[2-[(dimethylphosphinyl)methoxy]pyrimidin-5-yl]-6,7-dihydro-6-methyl-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one