(R)-1-((5'-bromo-6'-((S)-1-methoxyethyl)-[2,3'-bipyridin]-5-yl)methyl)pyrrolidin-3-ol

(S)-4-(3-(5-bromo-6-(1-methoxyethyl)pyridin-3-yl)benzyl)morpholine

(R)-tert-butyl 2-((4-(5-bromo-6-((S)-1-methoxyethyl)pyridin-3-yl)-1H-pyrazol-1-yl)methyl)pyrrolidine-1-carboxylate

(S)-benzyl 6-((5-bromo-6-(1-methoxyethyl)pyridin-3-yl)oxy)-2-azaspiro[3.3]heptane-2-carboxylate

(S)-4-(5-bromo-6-(1-methoxyethyl)pyridin-3-yl)-1-(methylimino)thiomorpholine 1-oxide

(8R,9aR)-8-(5-bromo-6-((S)-1-methoxyethyl)pyridin-3-yl)octahydropyrido[2,1-c][1,4]oxazine

(S)-3-bromo-5-(2-bromoethoxy)-2-(1-methoxyethyl)pyridine 1-oxide

(S)-3-bromo-5-iodo-2-(1-methoxyethyl)pyridine 1-oxide

benzyl 3-(((5-bromo-6-((S)-1-methoxyethyl)pyridin-3-yl)(methyl)amino)methyl)morpholine-4-carboxylate

(1R,3r)-3-(5-((7R,14R)-1-(difluoromethoxy)-6-((1-methoxycyclopropyl)methyl)-5-oxo-5,6,7,14-tetrahydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-11-yl)pyrimidin-2-yl)-1-(fluoromethyl)-3-hydroxycyclobutanecarbonitrile

(1R,3r)-3-(5-((7R,14R)-1-(difluoromethoxy)-6-((1-(fluoromethyl)cyclopropyl)methyl)-5-oxo-5,6,7,14-tetrahydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-11-yl)pyrimidin-2-yl)-1-(fluoromethyl)-3-hydroxycyclobutanecarbonitrile

(7R,14R)-1-(difluoromethoxy)-11-(2-((1s,3S)-3-(fluoromethyl)-1-hydroxy-3-methylcyclobutyl)pyrimidin-5-yl)-6-((1-methoxycyclopropyl)methyl)-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(1S,3s)-3-(5-((7R,14R)-1-(difluoromethoxy)-6-(2-methoxyethyl)-5-oxo-5,6,7,14-tetrahydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-11-yl)pyrimidin-2-yl)-3-hydroxy-1-methylcyclobutanecarbonitrile

(7R,14R)-11-(2-(1-aminocyclobutyl)pyrimidin-5-yl)-1-(difluoromethoxy)-6-(2-methoxyethyl)-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(1R,3r)-3-(5-((7R,14R)-1-(difluoromethoxy)-6-(((1s,3S)-3-methoxycyclobutyl)methyl)-5-oxo-5,6,7,14-tetrahydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-11-yl)pyrimidin-2-yl)-1-(fluoromethyl)-3-hydroxycyclobutanecarbonitrile

(1S,3s)-3-(5-((7R,14R)-1-(difluoromethoxy)-6-(((1s,3S)-3-fluorocyclobutyl)methyl)-5-oxo-5,6,7,14-tetrahydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-11-yl)pyrimidin-2-yl)-3-hydroxy-1-methylcyclobutanecarbonitrile

(1S,3r)-1-(cyclopropylmethyl)-3-(5-((7R,14R)-1-(difluoromethoxy)-6-methyl-5-oxo-5,6,7,14-tetrahydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-11-yl)pyrimidin-2-yl)-3-hydroxycyclobutanecarbonitrile

(7R,14R)-11-(2-(1-aminocyclobutyl)pyrimidin-5-yl)-1-(difluoromethoxy)-6-((1-methyl-1H-pyrazol-5-yl)methyl)-6,7-dihydro-7,14-methanobenzo[f]benzo[4,5]imidazo[1,2-a][1,4]diazocin-5(14H)-one

(7R,14R)-11-[(3S)-3-amino-2,3-dihydro-1,3-dimethyl-1H-pyrrolo[3,2-b]pyridin-6-yl]-1-(difluoromethoxy)-6,7-dihydro-6-methyl-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one

(7R,14R)-11-[(4R)-4-amino-3,4-dihydro-2,2-dimethyl-2H-pyrano[3,2-b]pyridin-7-yl]-1-(difluoromethoxy)-6,7-dihydro-6-methyl-7,14-Methanobenzimidazo[1,2-b][2,5]benzodiazocin-5(14H)--one